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Mellissia Officinalis and Atorvastatin on Serum Levels of Thyroid Hormones in Hypercholesterolemic Male Rats. J Research in Medical Sciences. (2013). 2, 6-12.
Abstracts
Artemisia dracunculus (Tarragon) of herbaceous, pereninial plant has several effective componds including: Flavnoids, Phytosterol, Sitosterol, Esteragol, Rutin and coumarin. Flavnoids have anti endrogenic and estrogenic effects. Coumarins have anti endrogenic effects too.
In this study the effects of hydroalchoholic extract of Artemisia dracunculus leaves on thyroid hormons (T₃,T₄) and TSH of made rats have been investigated.
This experimental study was performed on 40 wistar adult male rats weighting 200-230 g were divided into five groups.
The experimental groups recived 50,100, and 200 mg/kg of hydroalcholic extract of Artemisia dracunculus(tarragon) for 30 days orally. The sham group received only solvent (distilled water), and the control group was given nothing. Blood sampling was done from heart after the last administration.
T₃, T₄ and TSH hormones were measurement by radio immunoassay method. Then thyroid histopathological sections were prepared and studied. Statistical analysis was done using ANOVA and T-test by SPSS method.
The result of this study indicated these extracts administration decrease weight in experimental groups. In comparison with the control and sham group, however it was not significant.
Finally, These finalings suggest the Artemisia dracunculus extract has stimulatory effect on thyroid gland function and raises serum T₃ & T₄ levels.
ISLAMIC AZAD UNIVERSITY
Arsanjan branch
Faculty of scienc – Department of Biology
Thesis on Cellular Developmental Biology(M.S.C)
Subject
The effect of Hydro alcoholic Extract Artemisia Tarragon Leaf on Plasma Levels Thyroid Hormones (T₃, T₄) and TSH and Thyroid Tissue Changes in Adult Male Rat
By
Shokofeh Barootkoob
EVALUATED AND APPROVED BY THE THESIS COMMITTEE AS:
Alireza Yusefi (Ph.D) Advisor Ameneh khoshvaghty (Ph.D) Consulting Advisor
Heydar Aqababa (Ph.D) Judge Master
Head of Complementary Education
Research Administration
Heydar Aqababa(Ph.D)
Heydar Aqababa(Ph.D)
Summer 2014
ISLAMIC AZAD UNIVERSITY
Arsanjan Branch
Faculty of Basic Scenices -Department of Biology
Thesis on Cellular Developmental Biology(M.S.C)
Subject
The effect of Hydro alcoholic Extract Artemisia Tarragon Leaf on Plasma Levels Thyroid Hormones (T₃, T₄) and TSH and Thyroid Tissue Changes in Adult Male Rat
Thesis Advisor:
Alireza Yusefi (Ph.D)
Consulting Advisor:
Ameneh Khoshvaghty (Ph. D)
By:
Shokofeh Barootkoob
summer 2014
1 – World Health Organization
1 -Stragol
2- Methyl Chavicol
3- Cinnamic acid
1- Prostoglandin
1-Phytostrol
1- Isthmus
2-Acini
1-Colloid
1-Tetraiodothyronine
2-Triiodothyronine
3-Tyrosine
1-Iodide Trapping
1-Thyroglobulin
1-Adnocinmonophosphat
2-Pinocytosis
3-Monoiodotyrosine
1-Thyrotropin-Releasing hormone
1-Thyroid stimulating hormone
1-Hypothyroidism
2-hyperthyroidism
1-Hashimoto diseas
2-Graves
1-Hyperthyroidism
1-hypothyroidism
1-Dimethyl sulfoxide
1-Revolutions Per Minute
2-Fixation
3-Dehydration
1-Clearing
2 -Embedding
1- Catechol-o-methyltransferase
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الف
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114

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